UBAP2L - Wiki-CORONA

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
AGO2	argonaute RISC catalytic component 2	Pre-NOTCH Transcription and Translation MicroRNA (miRNA) biogenesis Ca2+ pathway Small interfering RNA (siRNA) biogenesis Post-transcriptional silencing by small RNAs Transcriptional regulation by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Regulation of RUNX1 Expression and Activity Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
ATXN1	ataxin 1			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
CHTOP	chromatin target of PRMT1	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
HAX1	HCLS1 associated protein X-1			Neutropenic disorders, including the following three diseases: Kostmann syndrome; Cyclic neutropenia; X-linked neutropenia/myelodysplasia
ITCH	itchy E3 ubiquitin protein ligase	Downregulation of ERBB4 signaling NOD1/2 Signaling Pathway Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus Degradation of GLI1 by the proteasome Hedgehog 'on' state RUNX1 regulates transcription of genes involved in differentiation of HSCs Negative regulators of DDX58/IFIH1 signaling Antigen processing: Ubiquitination & Proteasome degradation
KCNN3	potassium calcium-activated channel subfamily N member 3	Ca2+ activated K+ channels	Procaine Miconazole Trimebutine
MTNR1A	melatonin receptor 1A	Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events	Ramelteon Melatonin Resveratrol Agomelatine Tasimelteon
MTNR1B	melatonin receptor 1B	Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events	Ramelteon Melatonin Resveratrol Agomelatine Tasimelteon	Type II diabetes mellitus
NEDD4	NEDD4 E3 ubiquitin protein ligase	ISG15 antiviral mechanism Downregulation of ERBB4 signaling Regulation of PTEN localization Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
PLXNA2	plexin A2	Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions
POGZ	pogo transposable element derived with ZNF domain
PRMT1	protein arginine methyltransferase 1	RMTs methylate histone arginines TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Extra-nuclear estrogen signaling Estrogen-dependent gene expression	S-adenosyl-L-homocysteine
PRRC2A	proline rich coiled-coil 2A
SCIN	scinderin
SLC27A3	solute carrier family 27 member 3	Synthesis of very long-chain fatty acyl-CoAs
SMCP	sperm mitochondria associated cysteine rich protein
TCHH	trichohyalin	Formation of the cornified envelope
ZP3	zona pellucida glycoprotein 3	Interaction With Cumulus Cells And The Zona Pellucida

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