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Search Results for: PIGS

13 interactions involving PIGS - phosphatidylinositol glycan anchor biosynthesis class S found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
COL6A1 collagen type VI alpha 1 chain
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Signaling by PDGF
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • ECM proteoglycans
  • ECM proteoglycans
  • NCAM1 interactions
  • Collagen chain trimerization
  • Ossification of the posterior longitudinal ligament of spine (OPLL)
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
CPEB2 cytoplasmic polyadenylation element binding protein 2
CYB5D2 cytochrome b5 domain containing 2
GGT6 gamma-glutamyltransferase 6
  • Glutathione synthesis and recycling
  • Aflatoxin activation and detoxification
KRT40 keratin 40
  • Keratinization
  • Formation of the cornified envelope
KRTAP10-3 keratin associated protein 10-3
  • Keratinization
KRTAP10-8 keratin associated protein 10-8
  • Keratinization
NOTCH2NLA notch 2 N-terminal like A
PDYN prodynorphin
  • Opioid Signalling
  • G-protein activation
  • Peptide ligand-binding receptors
  • G alpha (i) signalling events
  • Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
SPP2 secreted phosphoprotein 2
  • Platelet degranulation
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Post-translational protein phosphorylation
TXNDC17 thioredoxin domain containing 17
ZMYND15 zinc finger MYND-type containing 15
ZNF701 zinc finger protein 701
  • Generic Transcription Pathway