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Search Results for: NINL

50 interactions involving NINL - ninein like found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
AKAP17A A-kinase anchoring protein 17A
APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2
APMAP adipocyte plasma membrane associated protein
AURKB aurora kinase B
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • SUMOylation of DNA replication proteins
  • RHO GTPases Activate Formins
  • Regulation of TP53 Activity through Phosphorylation
  • Mitotic Prometaphase
  • Regulation of MECP2 expression and activity
  • EML4 and NUDC in mitotic spindle formation
  • HESPERIDIN
  • AT9283
  • N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine
CBY2 chibby family member 2
CCDC130 coiled-coil domain containing 130
CCDC146 coiled-coil domain containing 146
CCDC33 coiled-coil domain containing 33
CCHCR1 coiled-coil alpha-helical rod protein 1
CLEC1B C-type lectin domain family 1 member B
  • GPVI-mediated activation cascade
DCTN5 dynactin subunit 5
  • MHC class II antigen presentation
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
ELOA elongin A
  • Formation of RNA Pol II elongation complex
  • Formation of HIV elongation complex in the absence of HIV Tat
  • Formation of HIV-1 elongation complex containing HIV-1 Tat
  • Pausing and recovery of Tat-mediated HIV elongation
  • Tat-mediated HIV elongation arrest and recovery
  • Tat-mediated elongation of the HIV-1 transcript
  • HIV elongation arrest and recovery
  • Pausing and recovery of HIV elongation
  • RNA Polymerase II Pre-transcription Events
  • TP53 Regulates Transcription of DNA Repair Genes
  • RNA Polymerase II Transcription Elongation
EWSR1 EWS RNA binding protein 1
  • Ewing's sarcoma
  • Myxoid liposarcoma
  • Clear cell sarcoma of soft tissue
  • Extraskeletal myxoid chondrosarcoma
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
  • PRC2 methylates histones and DNA
  • Oxidative Stress Induced Senescence
  • PKMTs methylate histone lysines
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
  • Transcriptional Regulation by E2F6
  • HCMV Early Events
FAM107A family with sequence similarity 107 member A
FAM161A FAM161 centrosomal protein A
  • Retinitis pigmentosa (RP)
GCC1 GRIP and coiled-coil domain containing 1
  • Retrograde transport at the Trans-Golgi-Network
GPKOW G-patch domain and KOW motifs
  • mRNA Splicing - Major Pathway
HAUS1 HAUS augmin like complex subunit 1
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
JUNB JunB proto-oncogene, AP-1 transcription factor subunit
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Interleukin-4 and Interleukin-13 signaling
  • NGF-stimulated transcription
KANSL1 KAT8 regulatory NSL complex subunit 1
  • HATs acetylate histones
KAT5 lysine acetyltransferase 5
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • DNA Damage/Telomere Stress Induced Senescence
  • HATs acetylate histones
  • HDR through Single Strand Annealing (SSA)
  • HDR through Homologous Recombination (HRR)
  • Sensing of DNA Double Strand Breaks
  • Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Resolution of D-loop Structures through Holliday Junction Intermediates
  • Nonhomologous End-Joining (NHEJ)
  • Homologous DNA Pairing and Strand Exchange
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Regulation of TP53 Activity through Phosphorylation
  • G2/M DNA damage checkpoint
  • Estrogen-dependent gene expression
  • Coenzyme A
  • S-Acetyl-Cysteine
KAT7 lysine acetyltransferase 7
  • HATs acetylate histones
KRT1 keratin 1
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • Zinc
  • Copper
  • Epidermolytic palmoplantar keratoderma (EPPK)
  • Ichthyosis hystrix, Curth-Macklin type
  • Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
  • Striate palmoplantar keratoderma
L3MBTL4 L3MBTL histone methyl-lysine binding protein 4
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
  • Antigen processing: Ubiquitination & Proteasome degradation
LZTS2 leucine zipper tumor suppressor 2
MAD1L1 mitotic arrest deficient 1 like 1
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
MBIP MAP3K12 binding inhibitory protein 1
  • HATs acetylate histones
MCM10 minichromosome maintenance 10 replication initiation factor
  • Activation of ATR in response to replication stress
  • Activation of the pre-replicative complex
PLK1 polo like kinase 1
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Polo-like kinase mediated events
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
  • Phosphorylation of the APC/C
  • Phosphorylation of Emi1
  • Condensation of Prophase Chromosomes
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • Regulation of PLK1 Activity at G2/M Transition
  • Activation of NIMA Kinases NEK9, NEK6, NEK7
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • Mitotic Metaphase/Anaphase Transition
  • Mitotic Telophase/Cytokinesis
  • Cyclin A/B1/B2 associated events during G2/M transition
  • The role of GTSE1 in G2/M progression after G2 checkpoint
  • AURKA Activation by TPX2
  • EML4 and NUDC in mitotic spindle formation
  • 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol
  • 3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide
  • 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE
  • 1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea
  • (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE
POLR3F RNA polymerase III subunit F
  • Cytosolic sensors of pathogen-associated DNA
  • RNA Polymerase III Chain Elongation
  • RNA Polymerase III Transcription Termination
  • RNA Polymerase III Abortive And Retractive Initiation
  • RNA Polymerase III Transcription Initiation From Type 1 Promoter
  • RNA Polymerase III Transcription Initiation From Type 1 Promoter
  • RNA Polymerase III Transcription Initiation From Type 2 Promoter
  • RNA Polymerase III Transcription Initiation From Type 2 Promoter
  • RNA Polymerase III Transcription Initiation From Type 3 Promoter
  • RNA Polymerase III Transcription Initiation From Type 3 Promoter
RBM41 RNA binding motif protein 41
RCOR3 REST corepressor 3
RGS2 regulator of G protein signaling 2
  • G alpha (q) signalling events
RIBC2 RIB43A domain with coiled-coils 2
SEC23B SEC23 homolog B, COPII coat complex component
  • Congenital dyserythropoietic anemias (CDAs)
SH2D4A SH2 domain containing 4A
SH3BP5L SH3 binding domain protein 5 like
SYT17 synaptotagmin 17
TCEANC transcription elongation factor A N-terminal and central domain containing
TNNT1 troponin T1, slow skeletal type
  • Striated Muscle Contraction
  • Nemaline myopathy
TSPYL4 TSPY like 4
UTP14A UTP14A small subunit processome component
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
ZFC3H1 zinc finger C3H1-type containing
ZFHX3 zinc finger homeobox 3
  • RUNX3 regulates CDKN1A transcription
ZNF250 zinc finger protein 250
  • Generic Transcription Pathway
ZNF417 zinc finger protein 417
  • Generic Transcription Pathway
ZNF426 zinc finger protein 426
  • Generic Transcription Pathway
ZNF646 zinc finger protein 646