Search Results for: JAKMIP1

Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
BOD1L1 biorientation of chromosomes in cell division 1 like 1
CLNK cytokine dependent hematopoietic cell linker
GABBR1 gamma-aminobutyric acid type B receptor subunit 1
  • Activation of G protein gated Potassium channels
  • G alpha (i) signalling events
  • Class C/3 (Metabotropic glutamate/pheromone receptors)
  • GABA B receptor activation
  • Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
  • Baclofen
  • Progabide
  • Gabapentin
  • Vigabatrin
  • Taurine
  • gamma-Aminobutyric acid
  • SGS-742
  • Arbaclofen
  • Arbaclofen Placarbil
HTRA3 HtrA serine peptidase 3
JAK1 Janus kinase 1
  • Interleukin-6 signaling
  • Interleukin-6 signaling
  • MAPK3 (ERK1) activation
  • MAPK1 (ERK2) activation
  • ISG15 antiviral mechanism
  • Interleukin-7 signaling
  • Interleukin-7 signaling
  • Other interleukin signaling
  • RAF/MAP kinase cascade
  • Interleukin-10 signaling
  • Interleukin-4 and Interleukin-13 signaling
  • IL-6-type cytokine receptor ligand interactions
  • Interferon gamma signaling
  • Regulation of IFNG signaling
  • Regulation of IFNG signaling
  • Interleukin-20 family signaling
  • Interleukin-15 signaling
  • Interleukin-15 signaling
  • Interleukin-35 Signalling
  • Interleukin-9 signaling
  • Interleukin-2 signaling
  • Interleukin-12 signaling
  • Interleukin-12 signaling
  • Interleukin-27 signaling
  • Interleukin-27 signaling
  • Interleukin-21 signaling
  • Interferon alpha/beta signaling
  • Interleukin receptor SHC signaling
  • Regulation of IFNA signaling
  • Regulation of IFNA signaling
  • Myricetin
  • 2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE
  • Ruxolitinib
  • Tofacitinib
  • Baricitinib
MKX mohawk homeobox
MRFAP1L1 Morf4 family associated protein 1 like 1
NKX2-1 NK2 homeobox 1
  • Choreoathetosis, hypothyroidism, and neonatal respiratory distress
TADA2B transcriptional adaptor 2B
  • HATs acetylate histones
  • Ub-specific processing proteases
TRMT44 tRNA methyltransferase 44 homolog
  • tRNA modification in the nucleus and cytosol
TYK2 tyrosine kinase 2
  • Interleukin-6 signaling
  • Interleukin-6 signaling
  • MAPK3 (ERK1) activation
  • MAPK1 (ERK2) activation
  • Other interleukin signaling
  • Interleukin-10 signaling
  • Interleukin-4 and Interleukin-13 signaling
  • IL-6-type cytokine receptor ligand interactions
  • Interleukin-20 family signaling
  • Interleukin-35 Signalling
  • Interleukin-12 signaling
  • Interleukin-12 signaling
  • Interleukin-23 signaling
  • Interleukin-23 signaling
  • Interleukin-27 signaling
  • Interleukin-27 signaling
  • Interferon alpha/beta signaling
  • Regulation of IFNA signaling
  • Regulation of IFNA signaling
  • 2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE
  • Tofacitinib
  • Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • AURKA Activation by TPX2
  • Regulation of localization of FOXO transcription factors