Search Results for: HYOU1

12 interactions involving HYOU1 - hypoxia up-regulated 1 found:

Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
CADM1 cell adhesion molecule 1
  • Adherens junctions interactions
  • Nectin/Necl trans heterodimerization
  • Nasopharyngeal cancer
DPYSL3 dihydropyrimidinase like 3
  • CRMPs in Sema3A signaling
IL1R1 interleukin 1 receptor type 1
  • Interleukin-10 signaling
  • Interleukin-1 signaling
  • Anakinra
  • SD118
  • OMS-103HP
IL1RL1 interleukin 1 receptor like 1
  • PIP3 activates AKT signaling
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • Interleukin-33 signaling
INPPL1 inositol polyphosphate phosphatase like 1
  • Synthesis of PIPs at the plasma membrane
  • Synthesis of IP3 and IP4 in the cytosol
  • Interleukin receptor SHC signaling
NXPE4 neurexophilin and PC-esterase domain family member 4
PPP2R1B protein phosphatase 2 scaffold subunit Abeta
  • Inhibition of replication initiation of damaged DNA by RB1/E2F1
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Integration of energy metabolism
  • PP2A-mediated dephosphorylation of key metabolic factors
  • DARPP-32 events
  • Degradation of beta-catenin by the destruction complex
  • Beta-catenin phosphorylation cascade
  • ERK/MAPK targets
  • ERKs are inactivated
  • MASTL Facilitates Mitotic Progression
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • CTLA4 inhibitory signaling
  • Platelet sensitization by LDL
  • Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • Misspliced GSK3beta mutants stabilize beta-catenin
  • S33 mutants of beta-catenin aren't phosphorylated
  • S37 mutants of beta-catenin aren't phosphorylated
  • S45 mutants of beta-catenin aren't phosphorylated
  • T41 mutants of beta-catenin aren't phosphorylated
  • APC truncation mutants have impaired AXIN binding
  • AXIN missense mutants destabilize the destruction complex
  • Truncations of AMER1 destabilize the destruction complex
  • RHO GTPases Activate Formins
  • RAF activation
  • Negative regulation of MAPK pathway
  • Regulation of TP53 Degradation
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • Mitotic Prometaphase
  • Cyclin D associated events in G1
  • Cyclin A/B1/B2 associated events during G2/M transition
  • Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
  • EML4 and NUDC in mitotic spindle formation
RBM7 RNA binding motif protein 7
SEL1L SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
  • Pre-NOTCH Processing in Golgi
  • ABC-family proteins mediated transport
  • Hedgehog ligand biogenesis
  • Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
  • Defective CFTR causes cystic fibrosis
  • ER Quality Control Compartment (ERQC)
TAGLN transgelin
TMEM245 transmembrane protein 245
TP53BP2 tumor protein p53 binding protein 2
  • Activation of PUMA and translocation to mitochondria
  • TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
  • TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
  • TP53 Regulates Transcription of Death Receptors and Ligands
  • Regulation of TP53 Activity through Association with Co-factors