CADM1 |
cell adhesion molecule 1 |
- Adherens junctions interactions
- Nectin/Necl trans heterodimerization
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DPYSL3 |
dihydropyrimidinase like 3 |
- CRMPs in Sema3A signaling
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IL1R1 |
interleukin 1 receptor type 1 |
- Interleukin-10 signaling
- Interleukin-1 signaling
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IL1RL1 |
interleukin 1 receptor like 1 |
- PIP3 activates AKT signaling
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- Interleukin-33 signaling
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INPPL1 |
inositol polyphosphate phosphatase like 1 |
- Synthesis of PIPs at the plasma membrane
- Synthesis of IP3 and IP4 in the cytosol
- Interleukin receptor SHC signaling
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NXPE4 |
neurexophilin and PC-esterase domain family member 4 |
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PPP2R1B |
protein phosphatase 2 scaffold subunit Abeta |
- Inhibition of replication initiation of damaged DNA by RB1/E2F1
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Integration of energy metabolism
- PP2A-mediated dephosphorylation of key metabolic factors
- DARPP-32 events
- Degradation of beta-catenin by the destruction complex
- Beta-catenin phosphorylation cascade
- ERK/MAPK targets
- ERKs are inactivated
- MASTL Facilitates Mitotic Progression
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- CTLA4 inhibitory signaling
- Platelet sensitization by LDL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Misspliced GSK3beta mutants stabilize beta-catenin
- S33 mutants of beta-catenin aren't phosphorylated
- S37 mutants of beta-catenin aren't phosphorylated
- S45 mutants of beta-catenin aren't phosphorylated
- T41 mutants of beta-catenin aren't phosphorylated
- APC truncation mutants have impaired AXIN binding
- AXIN missense mutants destabilize the destruction complex
- Truncations of AMER1 destabilize the destruction complex
- RHO GTPases Activate Formins
- RAF activation
- Negative regulation of MAPK pathway
- Regulation of TP53 Degradation
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- Mitotic Prometaphase
- Cyclin D associated events in G1
- Cyclin A/B1/B2 associated events during G2/M transition
- Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
- EML4 and NUDC in mitotic spindle formation
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RBM7 |
RNA binding motif protein 7 |
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SEL1L |
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase |
- Pre-NOTCH Processing in Golgi
- ABC-family proteins mediated transport
- Hedgehog ligand biogenesis
- Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
- Defective CFTR causes cystic fibrosis
- ER Quality Control Compartment (ERQC)
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TAGLN |
transgelin |
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TMEM245 |
transmembrane protein 245 |
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TP53BP2 |
tumor protein p53 binding protein 2 |
- Activation of PUMA and translocation to mitochondria
- TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
- TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
- TP53 Regulates Transcription of Death Receptors and Ligands
- Regulation of TP53 Activity through Association with Co-factors
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