HOOK1 - Wiki-CORONA

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
AKTIP	AKT interacting protein
ANK3	ankyrin 3	Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins COPI-mediated anterograde transport
CDC5L	cell division cycle 5 like	mRNA Splicing - Major Pathway
CDK4	cyclin dependent kinase 4	SCF(Skp2)-mediated degradation of p27/p21 Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence RMTs methylate histone arginines Transcriptional regulation of white adipocyte differentiation Cyclin D associated events in G1 Ubiquitin-dependent degradation of Cyclin D Ubiquitin-dependent degradation of Cyclin D PTK6 Regulates Cell Cycle Transcriptional regulation by RUNX2 Meiotic recombination Transcriptional regulation of granulopoiesis Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Purvalanol Alvocidib Palbociclib Ribociclib Abemaciclib	Glioma Malignant melanoma Cervical cancer
ERI3	ERI1 exoribonuclease family member 3
FAM160A2	family with sequence similarity 160 member A2
HOOK2	hook microtubule tethering protein 2
HOOK3	hook microtubule tethering protein 3
LMO2	LIM domain only 2	RUNX1 regulates transcription of genes involved in differentiation of HSCs		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
MRPL37	mitochondrial ribosomal protein L37	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
MYSM1	Myb like, SWIRM and MPN domains 1	Metalloprotease DUBs
S100A7	S100 calcium binding protein A7	Neutrophil degranulation Metal sequestration by antimicrobial proteins	Zinc 1-Anilino-8-Naphthalene Sulfonate
SYCE1	synaptonemal complex central element protein 1	Meiotic synapsis
TBC1D7	TBC1 domain family member 7	TBC/RABGAPs
TFIP11	tuftelin interacting protein 11	mRNA Splicing - Major Pathway
USP2	ubiquitin specific peptidase 2	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Ub-specific processing proteases Regulation of TP53 Degradation
VPS16	VPS16 core subunit of CORVET and HOPS complexes
VPS18	VPS18 core subunit of CORVET and HOPS complexes
VPS39	VPS39 subunit of HOPS complex
VPS41	VPS41 subunit of HOPS complex
ZNF250	zinc finger protein 250	Generic Transcription Pathway
ZNF785	zinc finger protein 785	Generic Transcription Pathway

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