| ARL15 |
ADP ribosylation factor like GTPase 15 |
|
|
|
| CASP3 |
caspase 3 |
- Activation of caspases through apoptosome-mediated cleavage
- SMAC (DIABLO) binds to IAPs
- SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
- Apoptotic cleavage of cellular proteins
- SMAC, XIAP-regulated apoptotic response
- Apoptosis induced DNA fragmentation
- Degradation of the extracellular matrix
- Signaling by Hippo
- NADE modulates death signalling
- Stimulation of the cell death response by PAK-2p34
- Caspase-mediated cleavage of cytoskeletal proteins
- Apoptotic cleavage of cell adhesion proteins
- Caspase activation via Dependence Receptors in the absence of ligand
- Caspase activation via Dependence Receptors in the absence of ligand
- Other interleukin signaling
|
- Minocycline
- 5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid
- Emricasan
- 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
- methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate
- 1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE
- [N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID
- 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID
- (1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
- (1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
- N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide
|
|
| CCNB3 |
cyclin B3 |
|
|
|
| CCNT1 |
cyclin T1 |
- Formation of RNA Pol II elongation complex
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- Pausing and recovery of Tat-mediated HIV elongation
- Tat-mediated HIV elongation arrest and recovery
- Tat-mediated elongation of the HIV-1 transcript
- HIV elongation arrest and recovery
- Pausing and recovery of HIV elongation
- Interactions of Tat with host cellular proteins
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- RNA Polymerase II Pre-transcription Events
- TP53 Regulates Transcription of DNA Repair Genes
- RNA polymerase II transcribes snRNA genes
- RNA polymerase II transcribes snRNA genes
- RNA Polymerase II Transcription Elongation
- Estrogen-dependent gene expression
|
|
|
| GPR173 |
G protein-coupled receptor 173 |
|
|
|
| GRIA1 |
glutamate ionotropic receptor AMPA type subunit 1 |
- COPII-mediated vesicle transport
- Activation of AMPA receptors
- Trafficking of AMPA receptors
- Trafficking of GluR2-containing AMPA receptors
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Cargo concentration in the ER
- Synaptic adhesion-like molecules
- Long-term potentiation
|
- Glutamic Acid
- Enflurane
- Isoflurane
- Ethanol
- Methoxyflurane
- Desflurane
- Sevoflurane
- Talampanel
- CX717
- Perampanel
- Fluciclovine (18F)
|
|
| GRIP1 |
glutamate receptor interacting protein 1 |
- Trafficking of GluR2-containing AMPA receptors
|
|
|
| GRM7 |
glutamate metabotropic receptor 7 |
- G alpha (i) signalling events
- Class C/3 (Metabotropic glutamate/pheromone receptors)
|
|
|
| HSPB1 |
heat shock protein family B (small) member 1 |
- VEGFA-VEGFR2 Pathway
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- MAPK6/MAPK4 signaling
- Extra-nuclear estrogen signaling
|
- Apatorsen
- Phenethyl Isothiocyanate
|
- Distal hereditary motor neuropathies (dHMN)
|
| MAGED4B |
MAGE family member D4B |
|
|
|
| MAP3K1 |
mitogen-activated protein kinase kinase kinase 1 |
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane
- FCERI mediated MAPK activation
- FCERI mediated MAPK activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
- MyD88 cascade initiated on plasma membrane
|
|
|
| RAB4A |
RAB4A, member RAS oncogene family |
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Synthesis of PIPs at the plasma membrane
- TBC/RABGAPs
- RAB geranylgeranylation
- MET receptor recycling
|
|
|
| SMAD2 |
SMAD family member 2 |
- Signaling by NODAL
- Signaling by NODAL
- Signaling by Activin
- Downregulation of TGF-beta receptor signaling
- TGF-beta receptor signaling activates SMADs
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- SMAD2/3 Phosphorylation Motif Mutants in Cancer
- SMAD4 MH2 Domain Mutants in Cancer
- SMAD2/3 MH2 Domain Mutants in Cancer
- TGFBR1 KD Mutants in Cancer
- Transcriptional regulation of pluripotent stem cells
- Ub-specific processing proteases
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
- FOXO-mediated transcription of cell cycle genes
- FOXO-mediated transcription of cell cycle genes
|
|
|
| SMURF1 |
SMAD specific E3 ubiquitin protein ligase 1 |
- Signaling by BMP
- Downregulation of TGF-beta receptor signaling
- TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
- Asymmetric localization of PCP proteins
- Hedgehog 'on' state
- Hedgehog 'on' state
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
- Regulation of RUNX3 expression and activity
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
| SPP1 |
secreted phosphoprotein 1 |
- Degradation of the extracellular matrix
- Signaling by PDGF
- Integrin cell surface interactions
- Integrin cell surface interactions
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- RUNX3 Regulates Immune Response and Cell Migration
- Post-translational protein phosphorylation
|
|
|
| TCEA2 |
transcription elongation factor A2 |
|
|
|
| TES |
testin LIM domain protein |
|
|
|