Wiki-CORONA

Search Results for: EIF4E2

51 interactions involving EIF4E2 - eukaryotic translation initiation factor 4E family member 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
ADAMTSL4 ADAMTS like 4
  • Defective B3GALTL causes Peters-plus syndrome (PpS)
  • O-glycosylation of TSR domain-containing proteins
  • Ectopia lentis
AMOTL2 angiomotin like 2
  • Signaling by Hippo
APP amyloid beta precursor protein
  • Platelet degranulation
  • ECM proteoglycans
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • G alpha (q) signalling events
  • G alpha (i) signalling events
  • Lysosome Vesicle Biogenesis
  • Formyl peptide receptors bind formyl peptides and many other ligands
  • TAK1 activates NFkB by phosphorylation and activation of IKKs complex
  • The NLRP3 inflammasome
  • Advanced glycosylation endproduct receptor signaling
  • Advanced glycosylation endproduct receptor signaling
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
  • Post-translational protein phosphorylation
  • TRAF6 mediated NF-kB activation
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Purinergic signaling in leishmaniasis infection
  • Amyloid fiber formation
  • Deferoxamine
  • Aluminium
  • Zinc
  • L-methionine (R)-S-oxide
  • Resveratrol
  • Phenserine
  • Tiomolibdate ion
  • CAD106
  • Mito-4509
  • Dimercaprol
  • Copper
  • Florbetaben (18F)
  • Florbetapir (18F)
  • Flutemetamol (18F)
  • Alzheimer's disease (AD)
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
  • ISG15 antiviral mechanism
CAB39 calcium binding protein 39
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • Neutrophil degranulation
CARD9 caspase recruitment domain family member 9
  • NOD1/2 Signaling Pathway
  • CLEC7A (Dectin-1) signaling
  • Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
CBY2 chibby family member 2
CCL24 C-C motif chemokine ligand 24
CDR2 cerebellar degeneration related protein 2
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
  • mTORC1-mediated signalling
  • Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
FBXO25 F-box protein 25
GIGYF1 GRB10 interacting GYF protein 1
HOMEZ homeobox and leucine zipper encoding
KRT13 keratin 13
  • Keratinization
  • Formation of the cornified envelope
  • White sponge nevus
KRT19 keratin 19
  • Keratinization
  • Formation of the cornified envelope
KRT20 keratin 20
  • Keratinization
  • Formation of the cornified envelope
KRT31 keratin 31
  • Keratinization
  • Formation of the cornified envelope
KRT40 keratin 40
  • Keratinization
  • Formation of the cornified envelope
KRTAP10-5 keratin associated protein 10-5
KRTAP10-8 keratin associated protein 10-8
  • Keratinization
KRTAP10-9 keratin associated protein 10-9
  • Keratinization
KRTAP4-12 keratin associated protein 4-12
LZTS2 leucine zipper tumor suppressor 2
MAGED1 MAGE family member D1
  • NRAGE signals death through JNK
  • Caspase activation via Dependence Receptors in the absence of ligand
MAPRE3 microtubule associated protein RP/EB family member 3
MDFI MyoD family inhibitor
MIPOL1 mirror-image polydactyly 1
MVK mevalonate kinase
  • Cholesterol biosynthesis
  • Activation of gene expression by SREBF (SREBP)
  • FARNESYL THIOPYROPHOSPHATE
  • Mevalonate kinase deficiency; Hyperimmunoglobulinemia D; Mevalonic aciduria
MYOG myogenin
  • Myogenesis
  • Myogenesis
NECAB2 N-terminal EF-hand calcium binding protein 2
NOTCH2NLA notch 2 N-terminal like A
PDE4DIP phosphodiesterase 4D interacting protein
PRDM14 PR/SET domain 14
  • Transcriptional regulation of pluripotent stem cells
REL REL proto-oncogene, NF-kB subunit
  • Activation of NF-kappaB in B cells
  • Hodgkin lymphoma
SAG S-antigen visual arrestin
  • Activation of the phototransduction cascade
  • Inactivation, recovery and regulation of the phototransduction cascade
  • Inactivation, recovery and regulation of the phototransduction cascade
  • Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
  • Retinitis pigmentosa (RP)
SP140 SP140 nuclear body protein
SPAG5 sperm associated antigen 5
SPRY2 sprouty RTK signaling antagonist 2
  • Spry regulation of FGF signaling
  • EGFR downregulation
TADA2A transcriptional adaptor 2A
  • HATs acetylate histones
TCF4 transcription factor 4
  • Myogenesis
  • Myogenesis
  • Pitt-Hopkins syndrome, including: Pitt-Hopkins syndrome; Pitt-Hopkins-like syndrome
TGFBRAP1 transforming growth factor beta receptor associated protein 1
TLE5 TLE family member 5, transcriptional modulator
  • Repression of WNT target genes
TMCC2 transmembrane and coiled-coil domain family 2
TRIM27 tripartite motif containing 27
  • SUMOylation of ubiquitinylation proteins
  • Regulation of PTEN stability and activity
  • Suppression of apoptosis
TRIM54 tripartite motif containing 54
UBXN11 UBX domain protein 11
USHBP1 USH1 protein network component harmonin binding protein 1
USP54 ubiquitin specific peptidase 54
ZBTB9 zinc finger and BTB domain containing 9