| APP |
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
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- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Phenserine
- Tiomolibdate ion
- CAD106
- Mito-4509
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
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| ATF7IP |
activating transcription factor 7 interacting protein |
- PKMTs methylate histone lysines
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| FAM83D |
family with sequence similarity 83 member D |
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| FRMD5 |
FERM domain containing 5 |
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| ITCH |
itchy E3 ubiquitin protein ligase |
- Downregulation of ERBB4 signaling
- NOD1/2 Signaling Pathway
- Activated NOTCH1 Transmits Signal to the Nucleus
- Activated NOTCH1 Transmits Signal to the Nucleus
- Degradation of GLI1 by the proteasome
- Hedgehog 'on' state
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Negative regulators of DDX58/IFIH1 signaling
- Antigen processing: Ubiquitination & Proteasome degradation
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| KAT2B |
lysine acetyltransferase 2B |
- Pre-NOTCH Transcription and Translation
- Pre-NOTCH Transcription and Translation
- YAP1- and WWTR1 (TAZ)-stimulated gene expression
- Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
- NOTCH1 Intracellular Domain Regulates Transcription
- NOTCH1 Intracellular Domain Regulates Transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- HATs acetylate histones
- Notch-HLH transcription pathway
- B-WICH complex positively regulates rRNA expression
- Physiological factors
- Metalloprotease DUBs
- RNA Polymerase I Transcription Initiation
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX3 regulates NOTCH signaling
- RUNX3 regulates NOTCH signaling
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH4 Intracellular Domain Regulates Transcription
- Estrogen-dependent gene expression
- Regulation of FOXO transcriptional activity by acetylation
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- Coenzyme A
- (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE
- N-(3-AMINOPROPYL)-2-NITROBENZENAMINE
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| KCNG3 |
potassium voltage-gated channel modifier subfamily G member 3 |
- Voltage gated Potassium channels
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| MYL9 |
myosin light chain 9 |
- EPHA-mediated growth cone collapse
- Sema4D induced cell migration and growth-cone collapse
- Smooth Muscle Contraction
- RHO GTPases activate PKNs
- RHO GTPases activate CIT
- RHO GTPases Activate ROCKs
- RHO GTPases activate PAKs
- RHO GTPases activate PAKs
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
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| NEK2 |
NIMA related kinase 2 |
- APC-Cdc20 mediated degradation of Nek2A
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- AURKA Activation by TPX2
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- 5-[(Z)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE
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| PDIA6 |
protein disulfide isomerase family A member 6 |
- XBP1(S) activates chaperone genes
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Post-translational protein phosphorylation
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| PHF20 |
PHD finger protein 20 |
- HATs acetylate histones
- Regulation of TP53 Degradation
- Regulation of TP53 Activity through Association with Co-factors
- Stabilization of p53
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| PLEKHA5 |
pleckstrin homology domain containing A5 |
- Synthesis of PIPs at the plasma membrane
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| TTI1 |
TELO2 interacting protein 1 |
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| YWHAG |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- AURKA Activation by TPX2
- Regulation of localization of FOXO transcription factors
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