ATE1 - Wiki-CORONA

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
ABRAXAS2	abraxas 2, BRISC complex subunit	Metalloprotease DUBs
ACADSB	acyl-CoA dehydrogenase short/branched chain	Branched-chain amino acid catabolism	L-Isoleucine Valproic Acid	Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
ALCAM	activated leukocyte cell adhesion molecule	L1CAM interactions
CTBP2	C-terminal binding protein 2	Repression of WNT target genes TCF7L2 mutants don't bind CTBP
FAM53B	family with sequence similarity 53 member B
INTS8	integrator complex subunit 8	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
NEDD8	NEDD8 ubiquitin like modifier	TGF-beta receptor signaling activates SMADs UCH proteinases Cargo recognition for clathrin-mediated endocytosis Neddylation Iron uptake and transport
NSMCE4A	NSE4 homolog A, SMC5-SMC6 complex component	SUMOylation of DNA damage response and repair proteins
NUP188	nucleoporin 188	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation
PLEKHA1	pleckstrin homology domain containing A1	Synthesis of PIPs at the plasma membrane	Citric Acid
RBM10	RNA binding motif protein 10			TARP syndrome
SUV39H1	suppressor of variegation 3-9 homolog 1	PKMTs methylate histone lysines SIRT1 negatively regulates rRNA expression
TIMM17B	translocase of inner mitochondrial membrane 17B	Mitochondrial protein import Mitochondrial protein import

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