Search Results for: AKAP8L

17 interactions involving AKAP8L - A-kinase anchoring protein 8 like found:

Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
ACTN2 actinin alpha 2
  • Platelet degranulation
  • Nephrin family interactions
  • Striated Muscle Contraction
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Ras activation upon Ca2+ influx through NMDA receptor
  • RAF/MAP kinase cascade
  • Assembly and cell surface presentation of NMDA receptors
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Long-term potentiation
AP1M1 adaptor related protein complex 1 subunit mu 1
  • Nef mediated downregulation of MHC class I complex cell surface expression
  • MHC class II antigen presentation
  • Lysosome Vesicle Biogenesis
  • Golgi Associated Vesicle Biogenesis
  • Neutrophil degranulation
ASF1B anti-silencing function 1B histone chaperone
BEX3 brain expressed X-linked 3
  • NADE modulates death signalling
C19orf57 chromosome 19 open reading frame 57
CDC6 cell division cycle 6
  • Transcription of E2F targets under negative control by DREAM complex
  • Activation of ATR in response to replication stress
  • CDC6 association with the ORC:origin complex
  • CDT1 association with the CDC6:ORC:origin complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
  • CDK-mediated phosphorylation and removal of Cdc6
  • G1/S-Specific Transcription
DHX9 DExH-box helicase 9
  • RIP-mediated NFkB activation via ZBP1
  • DEx/H-box helicases activate type I IFN and inflammatory cytokines production
  • mRNA Splicing - Major Pathway
EMD emerin
  • Nuclear Envelope Breakdown
  • Initiation of Nuclear Envelope (NE) Reformation
  • Depolymerisation of the Nuclear Lamina
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Emery-Dreifuss muscular dystrophy
EPHX3 epoxide hydrolase 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Integrin cell surface interactions
IL18R1 interleukin 18 receptor 1
  • Interleukin-37 signaling
  • Interleukin-18 signaling
LBR lamin B receptor
  • Cholesterol biosynthesis
  • Initiation of Nuclear Envelope (NE) Reformation
  • Regulation of MECP2 expression and activity
  • HEM skeletal dysplasia; Greenberg dysplasia
  • Pelger-Huet anomaly
OR7A17 olfactory receptor family 7 subfamily A member 17
  • Olfactory Signaling Pathway
PRKACA protein kinase cAMP-activated catalytic subunit alpha
  • PKA-mediated phosphorylation of CREB
  • PKA-mediated phosphorylation of key metabolic factors
  • Triglyceride catabolism
  • PKA activation
  • PKA activation in glucagon signalling
  • DARPP-32 events
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
  • Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
  • Rap1 signalling
  • Regulation of insulin secretion
  • Vasopressin regulates renal water homeostasis via Aquaporins
  • VEGFA-VEGFR2 Pathway
  • CREB1 phosphorylation through the activation of Adenylate Cyclase
  • CREB1 phosphorylation through the activation of Adenylate Cyclase
  • Interleukin-3, Interleukin-5 and GM-CSF signaling
  • Ion homeostasis
  • Degradation of GLI1 by the proteasome
  • Degradation of GLI2 by the proteasome
  • GLI3 is processed to GLI3R by the proteasome
  • Hedgehog 'off' state
  • Anchoring of the basal body to the plasma membrane
  • CD209 (DC-SIGN) signaling
  • MAPK6/MAPK4 signaling
  • RET signaling
  • AURKA Activation by TPX2
  • HDL assembly
  • ROBO receptors bind AKAP5
  • Loss of phosphorylation of MECP2 at T308
  • Regulation of MECP2 expression and activity
  • Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
  • ADORA2B mediated anti-inflammatory cytokines production
  • ADORA2B mediated anti-inflammatory cytokines production
  • FCGR3A-mediated IL10 synthesis
  • FCGR3A-mediated IL10 synthesis
  • Factors involved in megakaryocyte development and platelet production
  • Pentanal
  • Balanol Analog 2
  • Balanol Analog 8
  • Phosphonothreonine
  • Balanol Analog 1
  • 3,5-Diiodotyrosine
  • Balanol
  • Dexfosfoserine
  • S,S-(2-Hydroxyethyl)Thiocysteine
  • Hydroxyfasudil
  • (1S)-2-(1H-INDOL-3-YL)-1-{[(5-ISOQUINOLIN-6-YLPYRIDIN-3-YL)OXY]METHYL}ETHYLAMINE
  • (2S)-1-{[5-(1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-[(7AS)-7AH-INDOL-3-YL]PROPAN-2-AMINE
  • (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE
  • (2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
  • (1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE
  • N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE
  • 3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione
  • (4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE
  • N-METHYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE
  • (S)-1-PHENYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE
  • 6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE
  • (2R)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine
  • (2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]ethanamine
  • 4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE
  • (2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE
  • (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE
  • ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE
  • N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE
  • 5-(2-methylpiperazine-1-sulfonyl)isoquinoline
  • N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE
  • 2-[4-(3-METHYL-1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE
  • (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
  • 3-pyridin-4-yl-1H-indazole
  • 5-benzyl-1,3-thiazol-2-amine
  • 1-[4-(4-chlorophenyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
  • 1-[4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine
  • 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium
  • Fasudil
  • Myristic acid
  • (2S)-1-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-PHENYLPROPAN-2-AMINE
  • 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE
  • (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE
  • Ellagic Acid
PRPF40A pre-mRNA processing factor 40 homolog A
  • mRNA Splicing - Major Pathway
RASAL3 RAS protein activator like 3
  • Regulation of RAS by GAPs
TMPO thymopoietin