Influenza - Wiki-CORONA

Symbols	Name 1	Name 2	Pathways 1 Hide	Pathways 2 Hide	Drugs 1 Hide	Drugs 2 Hide	Diseases 1 Hide	Diseases 2 Hide
SLC25A6 and VIM	solute carrier family 25 member 6	vimentin	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Caspase-mediated cleavage of cytoskeletal proteins Striated Muscle Contraction Interleukin-4 and Interleukin-13 signaling Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy	Clodronic Acid	Artenimol Phenethyl Isothiocyanate
SLC25A6 and MID2	solute carrier family 25 member 6	midline 2	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane		Clodronic Acid
SLC25A6 and KRT31	solute carrier family 25 member 6	keratin 31	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Keratinization Formation of the cornified envelope	Clodronic Acid
SLC25A6 and KRTAP4-12	solute carrier family 25 member 6	keratin associated protein 4-12	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane		Clodronic Acid
SLC25A6 and PRSS23	solute carrier family 25 member 6	serine protease 23	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Clodronic Acid
SLC25A6 and TRIM23	solute carrier family 25 member 6	tripartite motif containing 23	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane		Clodronic Acid
SLC25A6 and CHEK2	solute carrier family 25 member 6	checkpoint kinase 2	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Regulation of TP53 Activity through Phosphorylation Regulation of TP53 Degradation Regulation of TP53 Activity through Methylation G2/M DNA damage checkpoint Stabilization of p53 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	Clodronic Acid	XL844		Li-Fraumeni syndrome, including: Classic Li-Fraumeni syndrome (LFS); LFS-like syndrome (LFSL)
SLC25A6 and TEKT4	solute carrier family 25 member 6	tektin 4	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane		Clodronic Acid
SLC25A6 and LZTS2	solute carrier family 25 member 6	leucine zipper tumor suppressor 2	Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane		Clodronic Acid
ANXA7 and APLP1	annexin A7	amyloid beta precursor like protein 1				Zinc Copper
APBB1 and APLP1	amyloid beta precursor protein binding family B member 1	amyloid beta precursor like protein 1	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks			Zinc Copper
APC and AGFG1	APC regulator of WNT signaling pathway	ArfGAP with FG repeats 1	Apoptotic cleavage of cellular proteins Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Deactivation of the beta-catenin transactivating complex Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane Misspliced GSK3beta mutants stabilize beta-catenin S33 mutants of beta-catenin aren't phosphorylated S37 mutants of beta-catenin aren't phosphorylated S45 mutants of beta-catenin aren't phosphorylated T41 mutants of beta-catenin aren't phosphorylated APC truncation mutants are not K63 polyubiquitinated APC truncation mutants have impaired AXIN binding AXIN missense mutants destabilize the destruction complex Truncations of AMER1 destabilize the destruction complex Ovarian tumor domain proteases	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis			Familial adenomatous polyposis Esophageal cancer Gastric cancer Cancer of the anal canal Gallbladder cancer
APLP1 and CDKN1A	amyloid beta precursor like protein 1	cyclin dependent kinase inhibitor 1A		SCF(Skp2)-mediated degradation of p27/p21 AKT phosphorylates targets in the cytosol Senescence-Associated Secretory Phenotype (SASP) DNA Damage/Telomere Stress Induced Senescence Constitutive Signaling by AKT1 E17K in Cancer Interleukin-4 and Interleukin-13 signaling TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Cyclin E associated events during G1/S transition Cyclin D associated events in G1 p53-Dependent G1 DNA Damage Response Cyclin A:Cdk2-associated events at S phase entry Transcriptional activation of cell cycle inhibitor p21 The role of GTSE1 in G2/M progression after G2 checkpoint TFAP2 (AP-2) family regulates transcription of cell cycle factors Transcriptional regulation by RUNX2 RUNX3 regulates CDKN1A transcription Transcriptional regulation of granulopoiesis FOXO-mediated transcription of cell cycle genes	Zinc Copper	Arsenic trioxide		Cervical cancer
APLP1 and GSTM4	amyloid beta precursor like protein 1	glutathione S-transferase mu 4		Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)	Zinc Copper	Glutathione Glutathione Sulfonic Acid S-Octylglutathione Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine 1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane S-Hexylglutathione
APLP1 and CDKN2C	amyloid beta precursor like protein 1	cyclin dependent kinase inhibitor 2C		Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1	Zinc Copper
APLP1 and HSPE1	amyloid beta precursor like protein 1	heat shock protein family E (Hsp10) member 1			Zinc Copper	Phenethyl Isothiocyanate
APLP1 and SETDB1	amyloid beta precursor like protein 1	SET domain bifurcated histone lysine methyltransferase 1		PKMTs methylate histone lysines	Zinc Copper
APLP1 and TSC22D1	amyloid beta precursor like protein 1	TSC22 domain family member 1			Zinc Copper
APLP1 and ZNF24	amyloid beta precursor like protein 1	zinc finger protein 24			Zinc Copper
APLP1 and STX5	amyloid beta precursor like protein 1	syntaxin 5		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Zinc Copper

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