CASP8AP2

Description		caspase 8 associated protein 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion PML Body
	Molecular Function	DNA Binding Transcription Corepressor Activity Death Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Peptidase Activator Activity Involved In Apoptotic Process SUMO Polymer Binding
	Biological Process	Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Cycle Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Fas Signaling Pathway Cellular Response To Mechanical Stimulus Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708) Major depressive disorder ( 29317602)
Interacting Genes		17 interacting genes: CALM1 CASP10 CASP8 CREBBP CREM CTBP2 FADD FAS GLUL MX1 NR3C2 PML SP100 SREBF2 TRAF2 TRIM21 UBE2I
Entrez ID		9994
HPRD ID		06048
Ensembl ID		ENSG00000118412
Uniprot IDs		Q9UKL3
PDB IDs		2LR8 6ANO 6AOZ 6AP0
Enriched GO Terms of Interacting Partners?
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