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LHX4

Description LIM homeobox 4
Image
GO Annotations Cellular Component
  • Nuclear Chromatin
  • Nucleus
Molecular Function
  • RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
  • Protein Binding
  • Methyl-CpG Binding
  • Sequence-specific DNA Binding
  • Metal Ion Binding
Biological Process
  • Placenta Development
  • Motor Neuron Axon Guidance
  • Animal Organ Morphogenesis
  • Medial Motor Column Neuron Differentiation
  • Neuron Differentiation
  • Negative Regulation Of Apoptotic Process
  • Positive Regulation Of Transcription By RNA Polymerase II
Pathways
  • Regulation of expression of SLITs and ROBOs
Drugs
Diseases
  • Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Interacting Genes 22 interacting genes: ADAMTSL4 AXIN1 CHCHD2 FDX2 GOLGA2 IFT172 IKZF1 KRT38 KRT40 LDB2 LONRF1 NRF1 ORC6 SH2D1A SNRNP25 SSX1 TCAP TCF4 TP53BP2 TXNDC5 UBQLN1 USP2
Entrez ID 89884
HPRD ID 03686
Ensembl ID ENSG00000121454
Uniprot IDs A0A0S2Z5S4 Q969G2
PDB IDs 5HOD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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