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RPS6KA4

Description ribosomal protein S6 kinase A4
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
Molecular Function
  • Magnesium Ion Binding
  • Protein Serine/threonine Kinase Activity
  • Ribosomal Protein S6 Kinase Activity
  • Protein Binding
  • ATP Binding
Biological Process
  • Negative Regulation Of Cytokine Production
  • Regulation Of Transcription, DNA-templated
  • Protein Phosphorylation
  • Inflammatory Response
  • Histone Phosphorylation
  • Positive Regulation Of CREB Transcription Factor Activity
  • Positive Regulation Of Histone Phosphorylation
  • Positive Regulation Of Histone Acetylation
  • Intracellular Signal Transduction
  • Histone H3-S10 Phosphorylation
  • Histone H3-S28 Phosphorylation
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Positive Regulation Of NF-kappaB Transcription Factor Activity
  • Interleukin-1-mediated Signaling Pathway
Pathways
  • Recycling pathway of L1
Drugs
  • Riboflavin Monophosphate
Diseases
GWAS
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 23128233)
  • Leprosy ( 22019778)
  • Offspring birth weight ( 31043758)
  • Primary biliary cholangitis ( 21399635)
  • Primary biliary cirrhosis ( 22961000)
  • Psoriasis ( 23143594)
Interacting Genes 9 interacting genes: ATF1 CREB1 FOS HMGN1 MAP2K1 MAPK1 MAPK14 MAPK3 NEDD4
Entrez ID 8986
HPRD ID 04677
Ensembl ID ENSG00000162302
Uniprot IDs A0PJF8 B4DPV1 E9PJN1 O75676
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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