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NKD2

Description NKD inhibitor of WNT signaling pathway 2
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Plasma Membrane
  • Basolateral Plasma Membrane
  • Lateral Plasma Membrane
  • Cytoplasmic Vesicle
  • Exocytic Vesicle
  • Cell Periphery
Molecular Function
  • Calcium Ion Binding
  • Protein Binding
  • Growth Factor Binding
  • Ubiquitin Protein Ligase Binding
  • Myosin Heavy Chain Binding
  • ATPase Binding
Biological Process
  • Exocytosis
  • Positive Regulation Of Protein Processing
  • Wnt Signaling Pathway
  • Negative Regulation Of Wnt Signaling Pathway
  • Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Golgi Vesicle Fusion To Target Membrane
  • Protein Localization To Plasma Membrane
  • Negative Regulation Of Canonical Wnt Signaling Pathway
  • Positive Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Pancreatic cancer ( 25086665)
  • QT interval ( 24952745)
  • Red cell distribution width ( 27863252 28957414)
Interacting Genes 9 interacting genes: ANAPC11 CDKN1A FBXO7 FUS GRB2 LNX1 RCHY1 TGFA VDR
Entrez ID 85409
HPRD ID 08483
Ensembl ID ENSG00000145506
Uniprot IDs Q969F2
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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