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PARP10

Description poly(ADP-ribose) polymerase family member 10
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GO Annotations Cellular Component
  • Nucleus
  • Nucleolus
  • Cytoplasm
  • Golgi Apparatus
  • Cytosol
Molecular Function
  • NAD+ ADP-ribosyltransferase Activity
  • Protein Binding
  • K63-linked Polyubiquitin Modification-dependent Protein Binding
  • Protein ADP-ribosylase Activity
Biological Process
  • Protein ADP-ribosylation
  • Negative Regulation Of Gene Expression
  • Regulation Of Chromatin Assembly
  • Translesion Synthesis
  • Negative Regulation Of NF-kappaB Transcription Factor Activity
  • NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway
  • Negative Regulation Of Viral Genome Replication
  • Negative Regulation Of Fibroblast Proliferation
  • Protein Poly-ADP-ribosylation
  • Protein Auto-ADP-ribosylation
  • Negative Regulation Of Protein K63-linked Ubiquitination
Pathways
  • Nicotinamide salvaging
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Menarche (age at onset) ( 25231870)
Interacting Genes 12 interacting genes: AURKA H2AC20 H2BC21 H3-3A H3C1 H4C1 IKBKG MYC PARP14 PCNA RAN UBC
Entrez ID 84875
HPRD ID 15100
Ensembl ID ENSG00000178685
Uniprot IDs B4E0C4 E9PK67 E9PNI7 Q53GL7
PDB IDs 2DHX 3HKV 5LX6 6FXI
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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