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NHEJ1

Description non-homologous end joining factor 1
Image
GO Annotations Cellular Component
  • Fibrillar Center
  • Nucleus
  • Nucleoplasm
  • DNA Ligase IV Complex
  • Nonhomologous End Joining Complex
Molecular Function
  • Protein Binding
  • DNA End Binding
Biological Process
  • Double-strand Break Repair Via Nonhomologous End Joining
  • Central Nervous System Development
  • Response To Ionizing Radiation
  • B Cell Differentiation
  • T Cell Differentiation
  • Positive Regulation Of Ligase Activity
Pathways
  • Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
  • Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation; NHEJ1 syndrome
GWAS
  • Height ( 25282103 25429064 31562340)
Interacting Genes 2 interacting genes: LIG4 XRCC4
Entrez ID 79840
HPRD ID 07784
Ensembl ID ENSG00000187736
Uniprot IDs Q9H9Q4
PDB IDs 2QM4 2R9A 3Q4F 3RWR 3SR2 3W03 6ERG 6ERH
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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