GSDMD

Description		gasdermin D
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Cytosol Plasma Membrane Specific Granule Lumen NLRP3 Inflammasome Complex Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidic Acid Binding Cardiolipin Binding
	Biological Process	Inflammatory Response Cellular Response To Extracellular Stimulus Pore Formation In Membrane Of Other Organism Defense Response To Bacterium Neutrophil Degranulation Innate Immune Response Pore Complex Assembly Positive Regulation Of Interleukin-1 Beta Secretion Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Protein Homooligomerization Pyroptosis
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Schizophrenia ( 31268507)
Interacting Genes		2 interacting genes: KCTD6 MFHAS1
Entrez ID		79792
HPRD ID		11014
Ensembl ID		ENSG00000104518
Uniprot IDs		P57764
PDB IDs		5NH1 5WQT 6AO4 6N9O
Enriched GO Terms of Interacting Partners?
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