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TNIP2

Description TNFAIP3 interacting protein 2
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytosol
Molecular Function
  • Protein Binding
  • Protein Kinase Binding
  • Polyubiquitin Modification-dependent Protein Binding
  • Metal Ion Binding
  • K63-linked Polyubiquitin Modification-dependent Protein Binding
Biological Process
  • Apoptotic Process
  • Inflammatory Response
  • I-kappaB Kinase/NF-kappaB Signaling
  • Protein Deubiquitination
  • CD40 Signaling Pathway
  • Toll-like Receptor 2 Signaling Pathway
  • Toll-like Receptor 3 Signaling Pathway
  • Toll-like Receptor 9 Signaling Pathway
  • Positive Regulation Of Macrophage Activation
  • Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Protein Stabilization
  • Positive Regulation Of B Cell Activation
  • Stress-activated MAPK Cascade
  • Interleukin-1-mediated Signaling Pathway
  • Cellular Response To Lipopolysaccharide
  • Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways
  • MAP3K8 (TPL2)-dependent MAPK1/3 activation
  • Ovarian tumor domain proteases
Drugs
Diseases
GWAS
  • Extrinsic epigenetic age acceleration ( 29374233)
  • Multiple sclerosis ( 31604244)
Interacting Genes 25 interacting genes: APP CDKN1A CLK1 EP300 FBXO25 FLNA IKBKG MAP3K8 MAPK1 MKNK1 NCOR2 NDUFB9 NFKB1 NFKB2 PSMD9 REL RELA SMARCD1 SMURF1 SRPK2 STK11 TEK TNFAIP3 TSG101 UBC
Entrez ID 79155
HPRD ID 18207
Ensembl ID ENSG00000168884
Uniprot IDs D6RGJ2 Q8NFZ5
PDB IDs 5H07
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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