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MIS12

Description MIS12 kinetochore complex component
Image
GO Annotations Cellular Component
  • MIS12/MIND Type Complex
  • Condensed Chromosome Kinetochore
  • Nuclear MIS12/MIND Complex
  • Cell
  • Nucleus
  • Cytosol
Molecular Function
  • Protein Binding
Biological Process
  • Mitotic Sister Chromatid Segregation
  • Chromosome Segregation
  • Protein Localization To Kinetochore
  • Cell Division
  • Attachment Of Mitotic Spindle Microtubules To Kinetochore
  • Kinetochore Assembly
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
  • Abstraction and mental flexibility ( 31596458)
  • Metabolite levels ( 23823483)
Interacting Genes 10 interacting genes: CBX3 CBX5 DSN1 HSP90AA1 KNL1 NDC80 NSL1 PMF1 SUGT1 ZWINT
Entrez ID 79003
HPRD ID 12379
Ensembl ID ENSG00000167842
Uniprot IDs A8K1M4 Q9H081
PDB IDs 5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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