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ZFP36
Description
ZFP36 ring finger protein
Image
GO Annotations
Cellular Component
Exosome (RNase Complex)
P-body
Nucleus
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
CCR4-NOT Complex
RISC-loading Complex
Dcp1-Dcp2 Complex
Ribonucleoprotein Complex
Molecular Function
DNA Binding
RNA Binding
MRNA Binding
Protein Binding
Enzyme Binding
Protein Kinase Binding
C-C Chemokine Binding
Heat Shock Protein Binding
MRNA 3'-UTR AU-rich Region Binding
Metal Ion Binding
RNA Polymerase Binding
14-3-3 Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
MAPK Cascade
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Poly(A) Tail Shortening
MRNA Catabolic Process
Response To Wounding
Regulation Of Keratinocyte Proliferation
Viral Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-independent Decay
Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Viral Transcription
MiRNA Mediated Inhibition Of Translation
P38MAPK Cascade
Response To Starvation
Regulation Of MRNA Stability
Cellular Response To Fibroblast Growth Factor Stimulus
Negative Regulation Of Interleukin-2 Biosynthetic Process
Positive Regulation Of Fat Cell Differentiation
Regulation Of Keratinocyte Differentiation
Negative Regulation Of Erythrocyte Differentiation
MRNA Transport
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
3'-UTR-mediated MRNA Destabilization
3'-UTR-mediated MRNA Stabilization
Cellular Response To Lipopolysaccharide
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Positive Regulation Of Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Regulation Of Keratinocyte Apoptotic Process
Negative Regulation Of Polynucleotide Adenylyltransferase Activity
Positive Regulation Of Intracellular MRNA Localization
Positive Regulation Of Gene Silencing By MiRNA
Pathways
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
Drugs
Diseases
GWAS
Interacting Genes
23 interacting genes:
APP
CCDC85B
CDK6
DCP1B
DHX36
DNAJB1
EDC3
EXOSC6
EXOSC8
FHL3
HMGB1
HOXC9
MAPK1
MAPKAPK2
NCL
NUP214
SFN
UPF2
XRN1
YWHAB
YWHAG
YWHAH
ZDHHC17
Entrez ID
7538
HPRD ID
01835
Ensembl ID
ENSG00000128016
Uniprot IDs
M0QY76
P26651
PDB IDs
4J8S
Enriched GO Terms of Interacting Partners
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