VLDLR

Description		very low density lipoprotein receptor
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GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Clathrin-coated Pit Membrane Integral Component Of Membrane Very-low-density Lipoprotein Particle Receptor Complex
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Calcium Ion Binding Protein Binding Very-low-density Lipoprotein Particle Receptor Activity Apolipoprotein Binding Very-low-density Lipoprotein Particle Binding Cargo Receptor Activity Reelin Receptor Activity Calcium-dependent Protein Binding
	Biological Process	Lipid Transport Receptor-mediated Endocytosis Signal Transduction Nervous System Development Axon Guidance Memory Cholesterol Metabolic Process Ventral Spinal Cord Development Low-density Lipoprotein Particle Receptor Catabolic Process Glycoprotein Transport Very-low-density Lipoprotein Particle Clearance Reelin-mediated Signaling Pathway Positive Regulation Of Protein Kinase Activity Dendrite Morphogenesis Positive Regulation Of Dendrite Development
Pathways		Reelin signalling pathway VLDLR internalisation and degradation VLDL clearance
Drugs		Lauric Acid
Diseases
GWAS		Alzheimer's disease (age of onset) ( 22005931) Cholesterol, total ( 24097068) Cytokine levels ( 31679650) Cytokine network levels (multivariate analysis) ( 31679650) Gambling ( 22780124) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 28334899) Systolic blood pressure ( 26969751) Total cholesterol levels ( 30275531) Vascular endothelial growth factor levels ( 26910538 27989323 31217265 21757650) White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621)
Interacting Genes		9 interacting genes: APOE CD36 CLU DAB1 LPL LRPAP1 MYLIP RELN SNX17
Entrez ID		7436
HPRD ID		01895
Ensembl ID		ENSG00000147852
Uniprot IDs		P98155 Q5VVF5
PDB IDs		1V9U 3DPR 6BYV
Enriched GO Terms of Interacting Partners?
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