BUB1

Description		BUB1 mitotic checkpoint serine/threonine kinase
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GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Nuclear Chromosome Outer Kinetochore Nucleoplasm Cytosol Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Protein Phosphorylation Apoptotic Process Regulation Of Sister Chromatid Cohesion Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Proliferation Viral Process Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Chromosome Segregation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
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Diseases
GWAS
Interacting Genes		18 interacting genes: AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BUB3 CDC20 CDK1 CRK EIF4EBP1 FBXO7 HDAC1 KNL1 PLK1 RAE1 RDH12 SVIL
Entrez ID		699
HPRD ID		03907
Ensembl ID		ENSG00000169679
Uniprot IDs		B4DYG2 O43683
PDB IDs		2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B
Enriched GO Terms of Interacting Partners?
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