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TACR1

Description tachykinin receptor 1
Image
GO Annotations Cellular Component
  • Cell
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Sperm Flagellum
  • Sperm Head
  • Sperm Midpiece
Molecular Function
  • Tachykinin Receptor Activity
  • Protein Binding
  • Substance P Receptor Activity
Biological Process
  • Inflammatory Response
  • G Protein-coupled Receptor Signaling Pathway
  • Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
  • Positive Regulation Of Cytosolic Calcium Ion Concentration
  • Tachykinin Receptor Signaling Pathway
  • Detection Of Abiotic Stimulus
  • Response To Pain
  • Regulation Of Uterine Smooth Muscle Contraction
  • Positive Regulation Of Flagellated Sperm Motility
Pathways
  • Tachykinin receptors bind tachykinins
  • G alpha (q) signalling events
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
Drugs
  • Aprepitant
  • Ketamine
  • Vapreotide
  • AV608
  • GW 597599
  • CP-122721
  • R673
  • SR 140333
  • Netupitant
  • Vestipitant
  • Vofopitant
Diseases
GWAS
  • Brain connectivity ( 23471985)
  • Chronotype ( 30696823)
  • Diisocyanate-induced asthma ( 25918132)
  • Nonunion in individuals with fractures ( 30680360)
  • Pursuit maintenance gain ( 29064472)
  • Seborrheic dermatitis ( 29203360)
  • Sexual dimorphism in anthropometric traits ( 23754948)
  • Weight ( 28552196)
Interacting Genes 5 interacting genes: GPRASP1 GRK5 TAC1 TAC3 TAC4
Entrez ID 6869
HPRD ID 01208
Ensembl ID ENSG00000115353
Uniprot IDs P25103
PDB IDs 2KS9 2KSA 2KSB 6E59 6HLL 6HLO 6HLP
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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