SOX3

Description		SRY-box transcription factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nuclear Transcription Factor Complex
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Sensory Organ Development Sex Determination Anatomical Structure Morphogenesis Hypothalamus Development Pituitary Gland Development Cell Differentiation Negative Regulation Of Neuron Differentiation Face Development Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Deactivation of the beta-catenin transactivating complex
Drugs
Diseases		Septo-optic dysplasia Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD) 46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS		Height ( 31562340)
Interacting Genes		12 interacting genes: AURKA CDKN2A DACH1 GLIS1 GLIS2 MYC NF2 NFIC NSD3 PAX6 TEAD2 TERT
Entrez ID		6658
HPRD ID		02432
Ensembl ID		ENSG00000134595
Uniprot IDs		P41225
PDB IDs
Enriched GO Terms of Interacting Partners?
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