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SLAMF1

Description signaling lymphocytic activation molecule family member 1
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • Cell Surface
  • Integral Component Of Membrane
  • Extracellular Exosome
Molecular Function
  • Virus Receptor Activity
  • Antigen Binding
  • Transmembrane Signaling Receptor Activity
  • Protein Binding
  • Identical Protein Binding
Biological Process
  • Adaptive Immune Response
  • Myeloid Dendritic Cell Activation Involved In Immune Response
  • Phagocytosis
  • Cell Adhesion
  • Positive Regulation Of Cell Proliferation
  • Negative Regulation Of Interleukin-12 Production
  • Negative Regulation Of Interleukin-6 Production
  • Negative Regulation Of Tumor Necrosis Factor Production
  • Innate Immune Response
  • Positive Regulation Of JNK Cascade
  • Lymphocyte Activation
  • Viral Entry Into Host Cell
  • Positive Regulation Of ERK1 And ERK2 Cascade
  • Negative Regulation Of CD40 Signaling Pathway
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
  • Itch intensity from mosquito bite ( 28199695)
  • Microalbuminuria ( 26631737)
  • Multiple sclerosis ( 31604244)
  • Schizophrenia (treatment resistant) ( 22479419)
Interacting Genes 6 interacting genes: FGR FYN INPP5D PTPN11 SH2D1A SH2D1B
Entrez ID 6504
HPRD ID 04603
Ensembl ID ENSG00000117090
Uniprot IDs Q13291
PDB IDs 1D4T 1D4W 1I3Z 1KA6 1KA7 1M27 2DZF 2IE9 2IFL 2IG5
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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