RPS12

Description		ribosomal protein S12
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GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Cytosol Membrane Cytosolic Small Ribosomal Subunit Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Facial morphology traits (63 three-dimensional facial segments) ( 29459680) Heel bone mineral density ( 30598549) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Type 2 diabetes nephropathy ( 21150874)
Interacting Genes		3 interacting genes: APP HMGB1 IKBKG
Entrez ID		6206
HPRD ID		04714
Ensembl ID		ENSG00000112306
Uniprot IDs		P25398
PDB IDs		4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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