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RELN
Description
reelin
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Plasma Membrane
Dendrite
Extracellular Matrix
Neuron Projection
Molecular Function
Serine-type Peptidase Activity
Metal Ion Binding
Lipoprotein Particle Receptor Binding
Very-low-density Lipoprotein Particle Receptor Binding
Biological Process
Cell Morphogenesis Involved In Differentiation
Neuron Migration
Proteolysis
Cell Adhesion
Axon Guidance
Central Nervous System Development
Brain Development
Long-term Memory
Associative Learning
Glial Cell Differentiation
Positive Regulation Of Neuron Projection Development
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Dendrite Development
Peptidyl-tyrosine Phosphorylation
Spinal Cord Patterning
Ventral Spinal Cord Development
Hippocampus Development
Cerebral Cortex Tangential Migration
Layer Formation In Cerebral Cortex
Positive Regulation Of TOR Signaling
Positive Regulation Of CREB Transcription Factor Activity
Reelin-mediated Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Response To Pain
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Behavior
Modulation Of Chemical Synaptic Transmission
Positive Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Synaptic Transmission, Glutamatergic
Long-term Synaptic Potentiation
Positive Regulation Of Dendritic Spine Morphogenesis
Positive Regulation Of Protein Tyrosine Kinase Activity
Positive Regulation Of Synapse Maturation
NMDA Glutamate Receptor Clustering
Postsynaptic Density Protein 95 Clustering
Receptor Localization To Synapse
Lateral Motor Column Neuron Migration
Positive Regulation Of Long-term Synaptic Potentiation
Positive Regulation Of Lateral Motor Column Neuron Migration
Regulation Of NMDA Receptor Activity
Positive Regulation Of Excitatory Postsynaptic Potential
Positive Regulation Of AMPA Receptor Activity
Pathways
Reelin signalling pathway
Drugs
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Alzheimer's disease (
20452100
)
Bitter alcoholic beverage consumption (
31046077
)
Intraocular pressure (
29785010
)
Metabolite levels (Pyroglutamine) (
23934736
)
Morning person (
30696823
)
Multiple sclerosis (age of onset) (
19010793
)
Night sleep phenotypes (
27126917
)
Otosclerosis (
19230858
)
Response to placebo treatment in childhood asthma (FVC change) (
31557306
)
Schizophrenia (
18282107
)
Sjögren's syndrome (
28076899
)
Sucrose liking (
31005972
)
Type 2 diabetes (
30054458
30297969
)
Venous thromboembolism adjusted for sickle cell variant rs77121243-T (
28203683
)
Interacting Genes
6 interacting genes:
DAB1
LRP8
PCDHA4
PCDHA6
SQSTM1
VLDLR
Entrez ID
5649
HPRD ID
02742
Ensembl ID
ENSG00000189056
Uniprot IDs
P78509
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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