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PARVA

Description parvin alpha
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Plasma Membrane
  • Focal Adhesion
  • Actin Cytoskeleton
  • Z Disc
  • Lamellipodium
Molecular Function
  • Actin Binding
  • Protein Binding
  • Cadherin Binding
Biological Process
  • Sprouting Angiogenesis
  • Outflow Tract Septum Morphogenesis
  • Establishment Or Maintenance Of Cell Polarity
  • Regulation Of Cell Shape
  • Cell Projection Assembly
  • Actin Cytoskeleton Reorganization
  • Heterotypic Cell-cell Adhesion
  • Substrate Adhesion-dependent Cell Spreading
  • Cilium Assembly
  • Actin-mediated Cell Contraction
  • Smooth Muscle Cell Chemotaxis
Pathways
  • Localization of the PINCH-ILK-PARVIN complex to focal adhesions
  • Cell-extracellular matrix interactions
  • Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS
  • Depressive symptoms (SSRI exposure interaction) ( 25649181)
  • Diisocyanate-induced asthma ( 25918132)
  • Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
  • Lung adenocarcinoma ( 28604730)
  • Mortality in heart failure ( 20400778)
Interacting Genes 15 interacting genes: ACTA1 APP ERO1B FERMT1 FERMT2 FERMT3 HSPB2 ILK LIMS1 MAP2K1 MLH1 NFE2L1 PXN UBE3A UBQLN1
Entrez ID 55742
HPRD ID 16283
Ensembl ID ENSG00000197702
Uniprot IDs Q9NVD7
PDB IDs 2K2R 2VZC 2VZD 2VZG 2VZI 3KMU 3KMW 3REP 6MIB
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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