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ALKBH5

Description alkB homolog 5, RNA demethylase
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Golgi Apparatus
  • Cytosol
  • Nuclear Speck
Molecular Function
  • RNA Binding
  • Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors
  • Oxidative RNA Demethylase Activity
  • Metal Ion Binding
  • RNA N6-methyladenosine Dioxygenase Activity
Biological Process
  • Response To Hypoxia
  • DNA Dealkylation Involved In DNA Repair
  • MRNA Processing
  • MRNA Export From Nucleus
  • Spermatogenesis
  • Cell Differentiation
  • Oxidative Single-stranded RNA Demethylation
  • Regulation Of MRNA Stability
Pathways
  • Reversal of alkylation damage by DNA dioxygenases
Drugs
Diseases
GWAS
  • Obesity-related traits ( 23251661)
Interacting Genes 1 interacting genes: CSNK2A1
Entrez ID 54890
HPRD ID 08621
Ensembl ID ENSG00000091542
Uniprot IDs Q6P6C2
PDB IDs 4NJ4 4NRM 4NRO 4NRP 4NRQ 4O61 4O7X 4OCT
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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