PKP1

Description		plakophilin 1
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GO Annotations	Cellular Component	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Intermediate Filament Plasma Membrane Cell-cell Junction Adherens Junction Desmosome Ficolin-1-rich Granule Membrane Messenger Ribonucleoprotein Complex
	Molecular Function	Protein Binding Lamin Binding Intermediate Filament Binding Structural Constituent Of Epidermis Cadherin Binding
	Biological Process	Cell-cell Junction Assembly Cell Adhesion Signal Transduction Positive Regulation Of Gene Expression Keratinization Neutrophil Degranulation Intermediate Filament Bundle Assembly Cornification Cell-cell Adhesion Negative Regulation Of MRNA Catabolic Process
Pathways		Apoptotic cleavage of cell adhesion proteins Neutrophil degranulation Keratinization Formation of the cornified envelope
Drugs
Diseases		Ectodermal dysplasia/skin fragility syndrome
GWAS		Panic disorder ( 19165232)
Interacting Genes		9 interacting genes: DSC1 DSG1 DSP GTF2IRD1 KRT14 KRT8 TNS2 UCHL5 VIM
Entrez ID		5317
HPRD ID		03579
Ensembl ID		ENSG00000081277
Uniprot IDs		A0A024R952 Q13835
PDB IDs		1XM9
Enriched GO Terms of Interacting Partners?
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