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PHYH

Description phytanoyl-CoA 2-hydroxylase
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Peroxisome
  • Peroxisomal Matrix
  • Cytosol
Molecular Function
  • Protein Binding
  • Ferrous Iron Binding
  • Carboxylic Acid Binding
  • L-ascorbic Acid Binding
  • Cofactor Binding
  • Phytanoyl-CoA Dioxygenase Activity
Biological Process
  • Fatty Acid Alpha-oxidation
  • 2-oxoglutarate Metabolic Process
  • Protein Targeting To Peroxisome
  • Isoprenoid Metabolic Process
  • 2-oxobutyrate Catabolic Process
  • Methyl-branched Fatty Acid Metabolic Process
Pathways
  • Alpha-oxidation of phytanate
  • Peroxisomal protein import
  • Peroxisomal protein import
  • TYSND1 cleaves peroxisomal proteins
Drugs
  • Antihemophilic factor, human recombinant
  • Vitamin C
Diseases
  • Refsum disease; Heredopathia atactica polyneuritiformis
GWAS
Interacting Genes 10 interacting genes: ACSL6 APP F8 FAM9B FKBP4 MAGEA11 PEX7 PHYHIP SIRPA TOM1L1
Entrez ID 5264
HPRD ID 03609
Ensembl ID ENSG00000107537
Uniprot IDs O14832
PDB IDs 2A1X
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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