PDK1

Description		pyruvate dehydrogenase kinase 1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Matrix Mitochondrial Pyruvate Dehydrogenase Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Protein Binding ATP Binding
	Biological Process	Glucose Metabolic Process Protein Phosphorylation Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Regulation Of Glucose Metabolic Process Glucose Homeostasis Hypoxia-inducible Factor-1alpha Signaling Pathway Negative Regulation Of Pyruvate Dehydrogenase Activity
Pathways		Regulation of pyruvate dehydrogenase (PDH) complex Signaling by Retinoic Acid
Drugs		4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE Dichloroacetic Acid
Diseases
GWAS		Blood protein levels ( 28240269) Erectile dysfunction in type 1 diabetes ( 22704111) Fasting plasma glucose ( 25187374)
Interacting Genes		15 interacting genes: AKT1 COL6A1 DLAT FGFR1 ITGB3 KAT2B LAMTOR5 PDHA1 PDK2 PIK3CA RPS6KB1 SGK1 USP4 XRCC6 YWHAQ
Entrez ID		5163
HPRD ID		03954
Ensembl ID		ENSG00000152256
Uniprot IDs		B7Z7N6 Q15118
PDB IDs		2Q8F 2Q8G 2Q8H
Enriched GO Terms of Interacting Partners?
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