ZBTB7A

Description		zinc finger and BTB domain containing 7A
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GO Annotations	Cellular Component	Nucleus Cytoplasm NuRD Complex Site Of Double-strand Break DNA-dependent Protein Kinase Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Corepressor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Activating Transcription Factor Binding Histone Acetyltransferase Binding SMAD Binding Metal Ion Binding Androgen Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Glycolytic Process Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus B Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Localization To Nucleus Regulation Of Apoptotic Process Erythrocyte Maturation Fat Cell Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Androgen Receptor Signaling Pathway Double-strand Break Repair Via Classical Nonhomologous End Joining Regulation Of Transcription Regulatory Region DNA Binding
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Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Pulse pressure ( 30578418) Reaction time ( 29844566) Red blood cell count ( 27863252)
Interacting Genes		19 interacting genes: AR BCL6 CRBN HOMEZ KHDRBS1 MBD3 NCOR1 NCOR2 PRKDC RELA SMAD4 SP1 SP3 SP4 UBE2I XRCC5 XRCC6 ZBTB48 ZMYND8
Entrez ID		51341
HPRD ID		10433
Ensembl ID		ENSG00000178951
Uniprot IDs		O95365
PDB IDs		2IF5 2NN2
Enriched GO Terms of Interacting Partners?
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