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PC

Description pyruvate carboxylase
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Mitochondrion
  • Mitochondrial Matrix
  • Cytosol
Molecular Function
  • Pyruvate Carboxylase Activity
  • Protein Binding
  • ATP Binding
  • Biotin Binding
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Pyruvate Metabolic Process
  • Gluconeogenesis
  • Lipid Metabolic Process
  • Biotin Metabolic Process
  • Negative Regulation Of Gene Expression
  • Viral RNA Genome Packaging
  • Positive Regulation By Host Of Viral Release From Host Cell
  • Positive Regulation By Host Of Viral Process
Pathways
  • Biotin transport and metabolism
  • Defective HLCS causes multiple carboxylase deficiency
  • Gluconeogenesis
Drugs
  • Pyruvic acid
  • Biotin
  • 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL
Diseases
  • Pyruvate carboxylase deficiency
GWAS
  • Bipolar disorder ( 21926972 31043756)
  • Familial squamous cell lung carcinoma ( 29924316)
  • HIV-1 susceptibility ( 22174851)
  • Urate levels ( 31578528)
Interacting Genes 3 interacting genes: GOT1 GOT2 MDH2
Entrez ID 5091
HPRD ID 02032
Ensembl ID ENSG00000173599
Uniprot IDs A0A024R5C5 P11498
PDB IDs 3BG3 3BG9
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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