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PRDX1

Description peroxiredoxin 1
Image
GO Annotations Cellular Component
  • Extracellular Space
  • Cell
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Melanosome
  • Extracellular Exosome
Molecular Function
  • RNA Binding
  • Peroxidase Activity
  • Protein Binding
  • Thioredoxin Peroxidase Activity
  • Identical Protein Binding
  • Cadherin Binding
Biological Process
  • Skeletal System Development
  • Retina Homeostasis
  • Response To Oxidative Stress
  • Cell Proliferation
  • Removal Of Superoxide Radicals
  • Natural Killer Cell Activation
  • Regulation Of Stress-activated MAPK Cascade
  • Cellular Response To Stress
  • Erythrocyte Homeostasis
  • Cellular Response To Oxidative Stress
  • Natural Killer Cell Mediated Cytotoxicity
  • Hydrogen Peroxide Catabolic Process
  • Leukocyte Activation
  • Cell Redox Homeostasis
  • Oxidation-reduction Process
  • Regulation Of NIK/NF-kappaB Signaling
Pathways
  • Detoxification of Reactive Oxygen Species
  • TP53 Regulates Metabolic Genes
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
  • Zinc
  • Copper
  • Artenimol
Diseases
GWAS
  • Blood protein levels ( 28240269)
  • Body mass index ( 26426971)
Interacting Genes 26 interacting genes: ABL1 ADH5 BTRC CALM1 CLEC4G EGFR EXOSC3 GAPDH IRF3 LUC7L MTRNR2L1 MYC MYD88 PPP2R1A PPP2R1B PRDX4 PTEN SESN1 SESN2 SH2D1B SMARCD1 SNCA TERF1 UBE3A VHL YWHAQ
Entrez ID 5052
HPRD ID 01458
Ensembl ID ENSG00000117450
Uniprot IDs A0A384NPQ2 Q06830
PDB IDs 2RII 3HY2 4XCS
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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