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NMT1

Description N-myristoyltransferase 1
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Mitochondrion
  • Cytosol
  • Plasma Membrane
  • Extrinsic Component Of Membrane
Molecular Function
  • Glycylpeptide N-tetradecanoyltransferase Activity
  • Protein Binding
  • Myristoyltransferase Activity
Biological Process
  • In Utero Embryonic Development
  • N-terminal Protein Myristoylation
  • N-terminal Peptidyl-glycine N-myristoylation
  • Regulation Of Rhodopsin Mediated Signaling Pathway
  • Cellular Ketone Metabolic Process
  • Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways
  • Late Phase of HIV Life Cycle
  • Inactivation, recovery and regulation of the phototransduction cascade
  • Activation, myristolyation of BID and translocation to mitochondria
Drugs
  • (1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone
Diseases
GWAS
  • Asthma ( 31619474)
  • Craniofacial microsomia ( 26853712)
  • Multisite chronic pain ( 31194737)
  • Pulse pressure ( 30578418)
  • Systolic blood pressure ( 30578418)
Interacting Genes 14 interacting genes: ANXA13 ARL5A CABP1 CABP2 CAPN2 CSNK2A1 FYN GNAZ HPCA LYN MARCKS NOS3 SRC TP53
Entrez ID 4836
HPRD ID 01187
Ensembl ID ENSG00000136448
Uniprot IDs P30419
PDB IDs 1RXT 3IU1 3IU2 3IWE 3JTK 4C2Y 4C2Z 5MU6 5NPQ 5O6H 5O6J 5O9S 5O9T 5O9U 5O9V 5UUT 6EHJ 6F56 6FZ2 6FZ3 6FZ5
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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