MYCN

Description		MYCN proto-oncogene, bHLH transcription factor
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GO Annotations	Cellular Component	Chromatin Nuclear Chromatin Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Kinase Binding Protein Dimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA
Pathways
Drugs
Diseases		Neuroblastoma Feingold syndrome
GWAS		Asthma or chronic obstructive pulmonary disease ( 24993907) Basal cell carcinoma ( 25855136) Height ( 31562340) Metabolite levels ( 23823483) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft palate ( 31609978) Pulmonary function (smoking interaction) ( 23284291) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Wilms tumor ( 22544364)
Interacting Genes		20 interacting genes: CSNK2A1 CSNK2A2 DOT1L EZH2 FBXW7 GRSF1 HUWE1 MAX MXD1 NEDD4 NMI NONO RUNX3 SIRT1 SP1 TRIM32 YAF2 YBX1 YEATS4 ZBTB17
Entrez ID		4613
HPRD ID		01278
Ensembl ID		ENSG00000134323
Uniprot IDs		A0A1W2PPD9 P04198 Q9H224
PDB IDs		5G1X
Enriched GO Terms of Interacting Partners?
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