ACADVL

Description		acyl-CoA dehydrogenase very long chain
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol Mitochondrial Membrane Mitochondrial Nucleoid
	Molecular Function	Fatty-acyl-CoA Binding Long-chain-acyl-CoA Dehydrogenase Activity Very-long-chain-acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Temperature Homeostasis Fatty Acid Beta-oxidation Response To Cold Energy Derivation By Oxidation Of Organic Compounds Epithelial Cell Differentiation Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase IRE1-mediated Unfolded Protein Response Negative Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Fatty Acid Oxidation Regulation Of Cholesterol Metabolic Process
Pathways		XBP1(S) activates chaperone genes Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Drugs
Diseases		Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
GWAS		Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: GPHN RPSA SIRT3 SOCS3
Entrez ID		37
HPRD ID		01940
Ensembl ID		ENSG00000072778
Uniprot IDs		B3KPA6 P49748
PDB IDs		2UXW 3B96
Enriched GO Terms of Interacting Partners?
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