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IMPDH1

Description inosine monophosphate dehydrogenase 1
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Secretory Granule Lumen
  • Azurophil Granule Lumen
  • Ficolin-1-rich Granule Lumen
Molecular Function
  • Nucleotide Binding
  • Nucleic Acid Binding
  • DNA Binding
  • RNA Binding
  • IMP Dehydrogenase Activity
  • Metal Ion Binding
Biological Process
  • GMP Biosynthetic Process
  • GTP Biosynthetic Process
  • Purine Ribonucleoside Monophosphate Biosynthetic Process
  • Neutrophil Degranulation
  • Lymphocyte Proliferation
  • Oxidation-reduction Process
Pathways
  • Neutrophil degranulation
  • Purine ribonucleoside monophosphate biosynthesis
Drugs
  • NADH
  • Mycophenolate mofetil
  • Ribavirin
  • Mycophenolic acid
  • Mercaptopurine
  • 6-Chloropurine Riboside, 5'-Monophosphate
  • VX-148
Diseases
  • Leber congenital amaurosis (LCR)
  • Retinitis pigmentosa (RP)
GWAS
Interacting Genes 2 interacting genes: GMNN HTRA1
Entrez ID 3614
HPRD ID 08853
Ensembl ID ENSG00000106348
Uniprot IDs B3KRZ3 P20839 Q6ZNB1
PDB IDs 1JCN
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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