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BABAM1

Description BRISC and BRCA1 A complex member 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Nuclear Body
  • BRCA1-A Complex
  • BRISC Complex
Molecular Function
  • Protein Binding
Biological Process
  • Double-strand Break Repair
  • Double-strand Break Repair Via Nonhomologous End Joining
  • Chromatin Organization
  • Cell Cycle
  • Response To Ionizing Radiation
  • Protein Deubiquitination
  • Positive Regulation Of DNA Repair
  • Cell Division
  • Protein K63-linked Deubiquitination
  • Signal Transduction Involved In G2 DNA Damage Checkpoint
Pathways
  • Metalloprotease DUBs
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
  • Cancer ( 27197191)
  • Cancer (pleiotropy) ( 27197191)
  • Epithelial ovarian cancer ( 25581431)
  • Mitochondrial DNA copy number ( 30704525)
Interacting Genes 7 interacting genes: AKT1 BABAM2 BRCA1 TERF2IP TNKS TRIM27 UBC
Entrez ID 29086
HPRD ID 13702
Ensembl ID ENSG00000105393
Uniprot IDs A0A024R7L2 J3KQS6 Q9NWV8
PDB IDs 6H3C
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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