ABR

Description		ABR activator of RhoGEF and GTPase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Cell Junction Axon Dendritic Spine Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Postsynaptic Density, Intracellular Component
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding
	Biological Process	Negative Regulation Of Cellular Extravasation G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Brain Development Actin Cytoskeleton Organization Response To Lipopolysaccharide Inner Ear Morphogenesis Positive Regulation Of Apoptotic Process Regulation Of Vascular Permeability Negative Regulation Of Neutrophil Degranulation Negative Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Modulation Of Chemical Synaptic Transmission Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Blood Vessel Remodeling Activation Of GTPase Activity
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Total cholesterol levels ( 30498476)
Interacting Genes		7 interacting genes: ADRA1A APP ECT2 ERBIN HRAS LNX1 PJA1
Entrez ID		29
HPRD ID		02649
Ensembl ID		ENSG00000159842
Uniprot IDs		B7Z2X0 B7Z683 B7Z7Z1 Q12979 Q6ZT60
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?