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SESN1

Description sestrin 1
Image No pdb structure
GO Annotations Cellular Component
  • Fibrillar Center
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • TORC2 Complex
  • GATOR2 Complex
Molecular Function
  • Protein Binding
  • Oxidoreductase Activity, Acting On Peroxide As Acceptor
  • Peroxiredoxin Activity
  • Leucine Binding
Biological Process
  • Positive Regulation Of Macroautophagy
  • Cellular Response To Amino Acid Starvation
  • Cellular Response To Glucose Starvation
  • Oxidation-reduction Process
  • Cellular Response To Amino Acid Stimulus
  • Cellular Response To Leucine
  • Reactive Oxygen Species Metabolic Process
  • Cellular Oxidant Detoxification
  • Regulation Of Response To Reactive Oxygen Species
  • Negative Regulation Of TORC1 Signaling
  • Cellular Response To Leucine Starvation
Pathways
  • Amino acids regulate mTORC1
Drugs
Diseases
GWAS
  • Birth weight ( 31043758)
  • Mean corpuscular volume ( 27863252)
  • Metabolite levels ( 23823483)
  • Offspring birth weight ( 31043758)
  • Prostate cancer ( 23535732)
Interacting Genes 3 interacting genes: MIOS PRDX1 WDR24
Entrez ID 27244
HPRD ID 07310
Ensembl ID ENSG00000080546
Uniprot IDs Q9Y6P5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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