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PLA2G2D

Description phospholipase A2 group IID
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
Molecular Function
  • Phospholipase A2 Activity
  • Calcium Ion Binding
  • Phospholipid Binding
  • Heparin Binding
  • Heparan Sulfate Proteoglycan Binding
  • Calcium-dependent Phospholipase A2 Activity
  • Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine)
  • Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
Biological Process
  • CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation
  • Phospholipid Metabolic Process
  • Phosphatidic Acid Biosynthetic Process
  • Inflammatory Response
  • Lipid Catabolic Process
  • Phosphatidylglycerol Acyl-chain Remodeling
  • Phosphatidylinositol Acyl-chain Remodeling
  • Phosphatidylserine Acyl-chain Remodeling
  • Phosphatidylcholine Acyl-chain Remodeling
  • Phosphatidylethanolamine Acyl-chain Remodeling
  • Negative Regulation Of T Cell Proliferation
  • Arachidonic Acid Secretion
Pathways
  • Acyl chain remodelling of PC
  • Acyl chain remodelling of PS
  • Acyl chain remodelling of PE
  • Acyl chain remodelling of PI
  • Acyl chain remodelling of PG
  • Synthesis of PA
Drugs
  • Lauric Acid
  • Stearic acid
Diseases
GWAS
  • group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
  • Obesity-related traits ( 23251661)
Interacting Genes 1 interacting genes: ADRB2
Entrez ID 26279
HPRD ID 07546
Ensembl ID ENSG00000117215
Uniprot IDs A0A087WZT4 Q9UNK4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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