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GART

Description phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
Image
GO Annotations Cellular Component
  • Cytosol
  • Extracellular Exosome
Molecular Function
  • Phosphoribosylamine-glycine Ligase Activity
  • Phosphoribosylformylglycinamidine Cyclo-ligase Activity
  • Phosphoribosylglycinamide Formyltransferase Activity
  • ATP Binding
  • Metal Ion Binding
Biological Process
  • Brainstem Development
  • Purine Nucleotide Biosynthetic Process
  • 'de Novo' IMP Biosynthetic Process
  • Glycine Metabolic Process
  • Purine Nucleobase Biosynthetic Process
  • Purine Ribonucleoside Monophosphate Biosynthetic Process
  • Response To Organic Substance
  • Response To Inorganic Substance
  • Cerebellum Development
  • Cerebral Cortex Development
  • Adenine Biosynthetic Process
  • Tetrahydrofolate Biosynthetic Process
Pathways
  • Purine ribonucleoside monophosphate biosynthesis
Drugs
  • Pemetrexed
  • Glycinamide Ribonucleotide
  • 10-CF3C(OH)2-DDACTHF
Diseases
GWAS
  • Crohn's disease ( 23128233)
  • Educational attainment ( 25201988)
  • Psoriasis ( 25854761)
Interacting Genes 3 interacting genes: KPNA2 PXN TRAF6
Entrez ID 2618
HPRD ID 00716
Ensembl ID ENSG00000159131
Uniprot IDs P22102 Q59HH3
PDB IDs 1MEJ 1MEN 1MEO 1NJS 1RBM 1RBQ 1RBY 1RBZ 1RC0 1RC1 1ZLX 1ZLY 2QK4 2V9Y 4EW1 4EW2 4EW3 4ZYT 4ZYU 4ZYV 4ZYW 4ZYX 4ZYY 4ZYZ 4ZZ0 4ZZ1 4ZZ2 4ZZ3 5J9F
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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