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POLR1A

Description RNA polymerase I subunit A
Image No pdb structure
GO Annotations Cellular Component
  • Nucleoplasm
  • RNA Polymerase I Complex
Molecular Function
  • RNA Polymerase I Activity
  • DNA Binding
  • Chromatin Binding
  • DNA-directed 5'-3' RNA Polymerase Activity
  • Protein Binding
  • Zinc Ion Binding
Biological Process
  • Transcription Initiation From RNA Polymerase I Promoter
  • Transcription Elongation From RNA Polymerase I Promoter
  • Termination Of RNA Polymerase I Transcription
  • Positive Regulation Of Gene Expression, Epigenetic
  • Negative Regulation Of Protein Localization To Nucleolus
Pathways
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • RNA Polymerase I Transcription Initiation
  • RNA Polymerase I Transcription Initiation
  • RNA Polymerase I Promoter Escape
  • RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS
  • Facial emotion recognition (sad faces) ( 28608620)
Interacting Genes 7 interacting genes: ANP32B NFKBIB NOLC1 POLR1E REL RRN3 TCF4
Entrez ID 25885
HPRD ID 10161
Ensembl ID ENSG00000068654
Uniprot IDs O95602
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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