GABBR1

Description		gamma-aminobutyric acid type B receptor subunit 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite G Protein-coupled Receptor Heterodimeric Complex Presynaptic Membrane Postsynaptic Membrane Schaffer Collateral - CA1 Synapse GABA-ergic Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled GABA Receptor Activity Protein Binding G Protein-coupled Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Gamma-aminobutyric Acid Signaling Pathway Regulation Of Postsynaptic Membrane Potential
Pathways		Activation of G protein gated Potassium channels G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) GABA B receptor activation Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Baclofen Progabide Gabapentin Vigabatrin Taurine gamma-Aminobutyric acid SGS-742 Arbaclofen Arbaclofen Placarbil
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 22412388) Height ( 28552196) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Nasopharyngeal carcinoma ( 19664746) Nicotine dependence ( 28440896) Platelet count ( 26805783) Schizophrenia ( 27922604) Ulna and radius bone mineral density ( 30172743) White blood cell count ( 27863252)
Interacting Genes		11 interacting genes: ATF5 CHFR CPEB2 GABBR2 GNAO1 JAKMIP1 KCNJ6 MAX NSF RGS4 YWHAZ
Entrez ID		2550
HPRD ID		04644
Ensembl ID		ENSG00000204681
Uniprot IDs		A0A1U9X7R0 Q59HG8 Q5SUJ9 Q8IW08 Q9UBS5
PDB IDs		4MQE 4MQF 4MR7 4MR8 4MR9 4MRM 4MS1 4MS3 4MS4 4PAS 6HKC
Enriched GO Terms of Interacting Partners?
Tagcloud ?