FZD2

Description		frizzled class receptor 2
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Focal Adhesion Integral Component Of Membrane Clathrin-coated Endocytic Vesicle Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Wnt-protein Binding PDZ Domain Binding Wnt-activated Receptor Activity
	Biological Process	Membranous Septum Morphogenesis Muscular Septum Morphogenesis Outflow Tract Morphogenesis G Protein-coupled Receptor Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway Sensory Perception Of Smell Neuron Differentiation Epithelial Cell Differentiation Non-canonical Wnt Signaling Pathway Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity Hard Palate Development Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Inner Ear Receptor Cell Development Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Beta-catenin Destruction Complex Disassembly
Pathways		TCF dependent signaling in response to WNT Class B/2 (Secretin family receptors) Ca2+ pathway Ca2+ pathway Asymmetric localization of PCP proteins Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Drugs
Diseases
GWAS		Pulse pressure ( 30224653)
Interacting Genes		2 interacting genes: DLG4 ROR2
Entrez ID		2535
HPRD ID		02813
Ensembl ID		ENSG00000180340
Uniprot IDs		Q14332 Q86UZ8
PDB IDs		6C0B
Enriched GO Terms of Interacting Partners?
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