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FPR1

Description formyl peptide receptor 1
Image No pdb structure
GO Annotations Cellular Component
  • Cell
  • Cytoplasm
  • Plasma Membrane
  • Integral Component Of Membrane
  • Secretory Granule Membrane
  • Azurophil Granule Membrane
  • Ficolin-1-rich Granule Membrane
Molecular Function
  • G Protein-coupled Receptor Binding
  • Complement Receptor Activity
  • G Protein-coupled Receptor Activity
  • N-formyl Peptide Receptor Activity
  • Scavenger Receptor Binding
  • Protein Binding
  • RAGE Receptor Binding
Biological Process
  • Activation Of MAPK Activity
  • Complement Receptor Mediated Signaling Pathway
  • Chemotaxis
  • Inflammatory Response
  • Signal Transduction
  • G Protein-coupled Receptor Signaling Pathway
  • Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
  • Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
  • Positive Regulation Of Cytosolic Calcium Ion Concentration
  • Nitric Oxide Mediated Signal Transduction
  • Cytokine-mediated Signaling Pathway
  • Neutrophil Degranulation
Pathways
  • G alpha (i) signalling events
  • Formyl peptide receptors bind formyl peptides and many other ligands
  • Interleukin-10 signaling
  • Neutrophil degranulation
Drugs
  • Nedocromil
Diseases
GWAS
  • Alopecia areata ( 25608926)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Tourette syndrome ( 30818990)
Interacting Genes 5 interacting genes: ACTG1 ANXA1 GNAI2 GRK2 SAA1
Entrez ID 2357
HPRD ID 00646
Ensembl ID ENSG00000171051
Uniprot IDs P21462
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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